This 16-bit noninverting bus transceiver uses two separate configurable power-supply rails. The SN74AVC16T245 is optimized to operate with V_CCA/V_CCB set at 1.4 V to 3.6 V. It is operational with V_CCA/V_CCB as low as 1.2 V. The A port is designed to track V_CCA. V_CCA accepts any supply voltage from 1.2 V to 3.6 V. The B port is designed to track V_CCB. V_CCB accepts any supply voltage from 1.2 V to 3.6 V. This allows for universal low-voltage bidirectional translation between any of the 1.2-V, 1.5-V, 1.8-V, 2.5-V, and 3.3-V voltage nodes.

The SN74AVC16T245 is designed for asynchronous communication between data buses. The device transmits data from the A bus to the B bus or from the B bus to the A bus, depending on the logic level at the direction-control (DIR) input.