This single-bit noninverting bus transceiver uses two separate configurable power-supply rails. The A port is designed to track V_CCA. V_CCA accepts any supply voltage from 1.65 V to 5.5 V. The B port is designed to track V_CCB. V_CCB accepts any supply voltage from 1.65 V to 5.5 V. This allows for universal low-voltage bidirectional translation between any of the 1.8-V, 2.5-V, 3.3-V, and 5-V voltage nodes.

The SN74LVC1T45 is designed for asynchronous communication between two data buses. The logic levels of the direction-control (DIR) input activate either the B-port outputs or the A-port outputs. The device transmits data from the A bus to the B bus when the B-port outputs are activated and from the B bus to the A bus when the A-port outputs are activated.